Pathology Image Detail

Caption

Mammary gland: the epithelium lining most acini is more prominent than normal. Most acini and ducts are mildly to moderately distended by an amorphous proteinaceous fluid. There is mild to moderate interstitial fibrosis. The mammary epithelium occasionally piles-up and shows moderate atypia. Numerous epithelial cells undergo apoptosis. A tripolar mitosis (arrowhead) is present.

Description

Atypical lobular hyperplasia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29278
Tumor Name
Mammary gland • hyperplasia - atypical - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
Atypical lobular hyperplasia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
STOCK Tg(Wap-BCL2)#Jag Tg(Wap-Tag)8Gmn
Strain Types
transgenic
General Note
This STOCK genetic background was a mixture of strains including at least NMRI, C57BL/6, and DBA/2.
Strain Synonyms
NMRI-Tg(WapSV40)(WapBcl2)#?
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown