Pathology Image Detail

Caption

Atypical lobular hyperplasia: mammary alveoli are lined by a one cell-thick low columnar epithelium with a few minute places where cells pile-up up to 2 cells-thick. The cells have a medium-size, oval, and hyperchromatic nucleus. Mitotic figures and apoptotic bodies are numerous. There is mild to moderate interstitial edema, with mild interstitial fibrosis and pleocellular inflammation.

Description

Atypical lobular hyperplasia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29279
Tumor Name
Mammary gland • hyperplasia - atypical - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
Atypical lobular hyperplasia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
STOCK Tg(Wap-BCL2)#Jag Tg(Wap-Tag)8Gmn
Strain Types
transgenic
General Note
This STOCK genetic background was a mixture of strains including at least NMRI, C57BL/6, and DBA/2.
Strain Synonyms
NMRI-Tg(WapSV40)(WapBcl2)#?
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown