Pathology Image Detail

Caption

Mammary gland: the mammary gland is expanded by a large, nodular, unencapsulated, densely cellular neoplasm with a prominent central area of necrosis and cavitation. Most of the neoplasm has an epithelial phenotype. However, large portions of the neoplasm (?40%) show areas of epithelial to mesenchymal transition (upper right portions of the neoplasm).

Description

Adenocarcinoma, solid, glandular, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

240 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29284
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, glandular, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
240 days