Pathology Image Detail

Caption

Glandular mammary adenocarcinoma with epithelial to mesenchymal transition: this photomicrograph represents a portion of the neoplasm that predominantly is composed of neoplastic cells with an epithelial phenotype forming glands. In addition, there is an area of epithelial to mesenchymal transition (upper left corner of the photomicrograph). Neoplastic cells with a spindloid phenotype can hardly be differentiated from stromal cells.

Description

Adenocarcinoma, solid, glandular, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

240 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29284
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, glandular, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
240 days