Pathology Image Detail

Caption

 Mammary gland: the mammary gland is effaced by a nodular, partly encapsulated, locally invasive, densely cellular neoplasm. This neoplasm is composed of solid areas with central cavitation (comedo pattern; towards the center). Areas suggestive of the early stages of epithelial to mesenchymal transition are present at the periphery of the neoplasm (arrowhead).

Description

 Adenocarcinoma, solid, comedo, mammary gland

Age at Necropsy

 unknown

Contributor

 Ward JM (J:107304)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29290
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, comedo, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown