Pathology Image Detail

Caption

Solid mammary carcinoma: the neoplasm is composed of large solid areas supported by a scant amount of fibrovascular stroma. Numerous neoplastic cells undergo apoptosis. Neoplastic cells are polygonal, with indistinct cell borders and a moderate amount of strongly amphophilic cytoplasm. The nucleus is central, oval, medium-size, slightly hypochromatic, with a clumped chromatin and 1-3 large acidophilic nucleoli Anisokaryosis and anisocytosis are moderate. Mitoses are numerous. Many neoplastic cells undergo apoptosis.

Description

Adenocarcinoma, solid, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29295
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown