Caption |
Mammary gland: most of the mammary gland shows moderate lobular hyperplasia which is characterized by an increase in the number of mammary acini which are mildly ectatic (lower left corner of the photomicrograph). In addition, multifocally, entire lobules show squamous metaplasia of their epithelium (upper right corner of the photomicrograph). The acini in these areas are filled with large rafts of "ghost" epithelial cells and they often rupture, resulting in the formation of a foreign-body type granulomatous reaction. There is also moderate interstitial fibrosis and lymphoplasmacytic inflammation surrounding the mammary lobules that have undergone squamous metaplasia. |
Description |
Carcinoma, adenosquamous, and squamous metaplasia, mammary gland |
Age at Necropsy |
unknown |
Notes |
Photomicrographs of this case illustrate the early stages of an adenosquamous carcinoma. |
Contributor |
Ward JM (J:107304) |
Pathologist |
Mikaelian I (J:94320) |
Method |
H&E |
