Pathology Image Detail

Caption

Mammary gland: hyperplasia, squamous metaplasia with the formation or large rafts of "ghost" epithelial cells, interstitial fibrosis, and interstitial lymphocytic and plasmacytic inflammation are prominent in this mammary lobule. In addition, a few neutrophils have transmigrated through the metaplastic mammary epithelium and are intermingled with the cornified debris that often expand the lumen of mammary acini.

Description

Carcinoma, adenosquamous, and squamous metaplasia, mammary gland

Age at Necropsy

unknown

Notes

Photomicrographs of this case illustrate the early stages of an adenosquamous carcinoma.

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29297
Tumor Name
Mammary gland • carcinoma - adenosquamous
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma, adenosquamous, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(Mt1-Hgf)#Lmb
Strain Types
transgenic
Strain Synonyms
FVB/N-TgN(MT-HGFSF)#Lmb
MT-HGF/SF
FVB/N-Tg(MT-HGFSF)#Lmb
FVB/N-Tg(Mt-HGFSF)#Lmb
FVB/N-Tg(Mt1-HGFSF)#Lmb
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown