Pathology Image Detail

Caption

Spindle cell carcinoma: this photomicrograph illustrates an epithelial area. As exemplified on this photomicrograph, cornification may be observed in neoplasms undergoing epithelial to mesenchymal transition. Cornification is characterized by neoplastic cells acquiring a more abundant and more acidophilic cytoplasm as well as more angular contours. Their nucleus is larger, more hypochromatic, and with a larger nucleolus than other neoplastic cells.

Description

Carcinoma, spindle cell, with epithelial areas, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29305
Tumor Name
Mammary gland • carcinoma - spindle cell
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma, spindle cell, with epithelial areas, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
CD-1-Tg(Wap-Mmp3)#Sym
Strain Types
transgenic
Strain Synonyms
CD1-Tg(WAPMmp3)#Mks
CD-1-Tg(WAP-Mmp3)#Sym
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown