Pathology Image Detail

Caption	Mammary gland: a mammary lobule is greatly expanded. The ductal portions of the lobule are prominent and surrounded by prominent sclerosis. The acini are hyperplastic and are surrounded by lesser sclerosis. Cells in the ducts pile-up disorderly up to 3 cells-thick.
Description	Ductal carcinoma in situ, with sclerosis, mammary gland
Age at Necropsy	unknown
Notes	These lesions are very unique and are difficult to categorize. As indicated by the MMHCC panel of pathologists, these lesions have similarities with the human entity known as "sclerosing adenosis". However, they also differ from sclerosing adenosis of man in that the mitotic rate is higher, cells lining the ducts pile-up disorderly, there is squamous differentiation, and atypia is more prominent.
Contributor	Ward JM (J:107304)
Pathologist	Mikaelian I (J:94320)
Method	H&E