Pathology Image Detail

Caption

Mammary adenocarcinoma: this photomicrograph illustrates the morphology of the neoplasm towards its' center. Large blood-filled vascular spaces are present. Neoplastic cells form nests and trabeculae that often undergo cystic degeneration and are supported by a moderate amount of loose fibrovascular stroma. There are two types of neoplastic cells: (1) there are large polygonal cells with a moderate amount of pale acidophilic cytoplasm and a large central hypochromatic round to oval nucleus; (2) there are small polygonal cells with a small amount of amphophilic cytoplasm and a small hyperchromatic oval nucleus. Cells intermediate between these two phenotypes are also present. Anisokaryosis and anisocytosis are mild. Mitoses are rare.

Description

Adenocarcinoma, complex, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29309
Tumor Name
Mammary gland • adenocarcinoma - complex
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, complex, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
CD-1-Tg(Wap-Mmp3)21Sym
Strain Types
transgenic
Strain Synonyms
CD1-Tg(WAPMmp3)M2-21Mks
CD-1-Tg(WAP-Mmp3)21Sym
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown