Caption |
Atypical lobular hyperplasia: the interlobular and intralobular ducts are lined by two types of cells: (1) a one cell-thick layer of attenuated to low cuboidal cells that are reminiscent of myoepithelial cells; (2) a 2-4 cells-thick layer of cuboidal to polygonal cells. The acini form nests that are composed of cells that are larger, with a more acidophilic cytoplasm, and a larger and more hypochromatic nucleus than cells that line the ducts. Central cavitation and the formation of small slit-like lumens are common in the acinar areas. There is moderate interstitial fibrosis with mild pleocellular inflammation. |
