Pathology Image Detail

Caption

Mammary gland: the lumen of mammary ducts (predominantly) and acini is moderately expanded by a strongly acidophilic proteinaceous material that also contains a few clusters of desquamated cells. The epithelium lining these ducts and acini is hypercellular and columnar and it forms a few minute papillary projections. Cells lining these ducts have a larger nucleus than what is expected for the normal mammary gland.

Description

Hyperplasia, atypical, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29315
Tumor Name
Mammary gland • hyperplasia - atypical
Treatment Type
None (spontaneous)
Tumor Synonyms
Hyperplasia, atypical, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(WapNotch4)10Rnc/J
Strain Types
transgenic
General Note
The transgene integrated into the X chromosome.
Strain Synonyms
FVB/N-TgN(WapNotch4)10Rnc
FVB/N-Tg(WapInt3)10Rnc
FVB/N-TgN(WapInt3)10Rnc
Int3
FVB-Notch4
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown