Pathology Image Detail

Caption

Mammary gland: the mammary gland is markedly diffusely enlarged by markedly hyperplastic acini and ducts. In adddition, there are multifocal areas of carcinoma in situ (*). These areas are characterized by epithelial cells piling-up in the ducts and acini, dilation of the lumen of the ducts and acini, and mild to moderate interstitial fibrosis. In addition, there is prominent abrupt cornification (C) in the lumen of a moderate number of ducts and acini, resulting in the formation of large rafts of "ghost" cells.

Description

Carcinoma in situ and hyperplasia, mammary gland

Age at Necropsy

unknown

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29322
Tumor Name
Mammary gland • hyperplasia
Treatment Type
None (spontaneous)
Tumor Synonyms
hyperplasia, mammary gland
severe ductal and acinar hyperplasia
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(MMTV-Fgf7)1Led
Strain Types
transgenic
Strain Synonyms
MMTV-kgf
FVB/N-Tg(MMTV-Fgf7)#Led
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown