Caption |
Mammary gland: the mammary gland is effaced and expanded by a large, nodular, encapsulated, well-delineated, densely cellular neoplasm. This neoplasm is composed of coalescing trabeculae supported by a moderate amount of hyalinized fibrovascular stroma. This photomicrograph illustrates a portion of the neoplasm where a few glands are formed. Some glands are mildly ectatic. A few adipocytes have been entrapped in the neoplasm. |
Description |
Adenocarcinoma, solid, with secondary lumens, mammary gland |
Age at Necropsy |
330 days |
Notes |
This neoplasm arose in a mouse that was bitransgenic for Tgfa and Notch4. The phenotype of this neoplasm is consistent with that of a neoplasm arising in a mouse transgenic for Notch4. |
Contributor |
Ward JM (J:107304) |
Pathologist |
Mikaelian I (J:94320) |
Method |
H&E |
