Pathology Image Detail

Caption	Mammary gland: a few secondary lumens are present in the trabeculae located at the periphery of the neoplasm. Neoplastic cells are medium-size, cuboidal to polygonal, with distinct cell borders, and a moderate amount of acidophilic cytoplasm. The nucleus is central, round to oval, and hyperchromatic. Anisokaryosis and anisocytosis are minimal.
Description	Adenocarcinoma, solid, with secondary lumens, mammary gland
Age at Necropsy	330 days
Notes	This neoplasm arose in a mouse that was bitransgenic for Tgfa and Notch4. The phenotype of this neoplasm is consistent with that of a neoplasm arising in a mouse transgenic for Notch4.
Contributor	Ward JM (J:107304)
Pathologist	Mikaelian I (J:94320)
Method	H&E