Caption |
Solid mammary adenocarcinoma: this photomicrograph illustrates an area of invasion in the mammary fat pad. The invasive portions of the neoplasm form small contoured and anastomosed glands with an inconspicuous lumen and they are surrounded by a mild scirrhous reaction. The center of some of the solid areas has undergone liquefactive necrosis (comedo pattern). Neoplastic cells are low columnar to polygonal, with indistinct cell borders and a moderate amout of acidophilic cytoplasm. The nucleus is basal, oval, medium-size, hypochromatic, and generally oriented in the long axis of the cell (at right angle with the basement membrane). Anisokaryosis and anisocytosis are mild. A few mitoses are present. |
