Pathology Image Detail

Caption

Mammary gland: there is, within an hyperplastic alveolar nodule, a small, densely cellular, unencapsulated, expensile, neoplasm (arrowheads). This neoplasm is composed of closely packed tubules and solid areas supported by a scant amount of fibrovascular stroma. Neoplastic cells are cuboidal to polygonal, with indistinct cell borders and a moderate amount of homogeneous acidophilic cytoplasm. The nucleus is central, round, normochromatic, and with a small basophilic nucleolus. Anisokaryosis and anisocytosis are mild. A few mitoses are present (arrowheads). A small to moderate number of inflammatory cells, including pigment-laden macrophages, infiltrates the connective tissue in the hyperplastic alveolar nodule.

Description

Adenoma, tubular, arising in an hyperplastic alveolar nodule, mammary gland

Age at Necropsy

210 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29372
Tumor Name
Mammary gland • hyperplasia - alveolar
Treatment Type
None (spontaneous)
Tumor Synonyms
hyperplastic alveolar nodule, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
210 days