Pathology Image Detail

Caption

Mammary gland: the mammary gland is expanded by a small, unenencapsulated, densely cellular, expensile neoplasm arising in an hyperplastic alveolar nodule. The neoplasm is composed of solid areas with secondary lumen and a few closely-packed glands that are lined by a one cell-thick cuboidal epithelium and are supported by a scant amount of fibrovascular stroma. Epithelial cells in the hyperplastic alveolar nodule (in the right and lower right portions of the photomicrograph) show more atypia than generally observed in typical hyperplastic alveolar nodules. Also, the contours of the alveoli in the hyperplastic alveolar nodule are more irregular than typically observed in an hyperplastic alveolar nodule. However, cells do not pile-up disorderly and the overall pattern of the normal mammary gland can still be identified.

Description

Adenoma, solid and tubular, arising in an hyperplastic alveolar nodule, mammary gland

Age at Necropsy

210 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29375
Tumor Name
Mammary gland • hyperplasia - alveolar
Treatment Type
None (spontaneous)
Tumor Synonyms
hyperplastic alveolar nodule, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB-Tg(WapTgfa)215Bri
Strain Types
transgenic
Strain Synonyms
FVB-Tg(WapTgfa)#Eps
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
210 days