Caption |
Solid and tubular adenoma of the mammary gland: this photomicrograph illustrates a peripheral portion of the neoplasm where there is a small group of large cells that are columnar and have a more abundant and more acidophilic cytoplasm than most neoplastic cells. These cells undergo squamous metaplasia (*) that is not associated with the presence of trichohyalin or keratohyalin granules. The other neoplastic cells are polygonal, with indistinct cell borders and a moderate amount of amphophilic cytoplasm. The nucleus is central, round, normochromatic, round, and with a small basophilic nucleolus. Anisokaryosis and anisocytosis overall are mild. Mitoses are numerous. |
