Pathology Image Detail

Caption

Mammary gland: the neoplasm is composed of thick branching trabeculae with a radial orientation separated by a moderate amount of fibrovascular stroma. The trabeculae form massive fronds at the periphery of the neoplasm with also large solid areas. The trabeculae are cavitated towards the center of the neoplasm where they form ducts lined by a 5-10 cells-thick epithelium.

Description

Type P tumor, mammary gland

Age at Necropsy

128 days

Contributor

Churchill GA (J:112750)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29395
Tumor Name
Mammary gland • tumor - type P
Treatment Type
None (spontaneous)
Tumor Synonyms
Type P tumor, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(Wnt1)1Hev/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated on a C57BL/6 x SJL background. It was subsequently backcrossed onto FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(Wnt1)1Hev/J
FVB-Wnt1
FVB/NJ-Tg(Wnt1)1Hev/J; FVB-Wnt1
MMTV-Wnt-1 FVB/NJ
MMTV-Wnt-1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
128 days