Caption |
Solid/comedo carcinoma: as exemplified by this photomicrograph, the center of the neoplasm comprised large fibrotic areas. These areas are interpreted as scarred areas that developed secondary to necrosis. |
Description |
Adenocarcinoma, solid, trabecular, mammary gland |
Age at Necropsy |
364 days |
Notes |
This tumor is not typical of a tumor arising in a mouse transgenic for Wnt1. The genotype of this mouse was checked thrice. Mice transgenic for Wnt1 generally develop type P mammary tumors that are characterized by the formation of structures resembling terminal end buds and ducts, as well as prominent myoepithelial differentiation. All these features are missing from this neoplasm. |
Contributor |
Churchill GA (J:112750) |
Pathologist |
Mikaelian I (J:94320) |
Method |
H&E |
