Pathology Image Detail

Caption

Mammary gland: the mammary gland is expanded and replaced by a nodular, encapsulated, densely cellular, multilobular neoplasm. This neoplasm is composed of large lobules separated by areas of early epithelial to mesenchymal transition (arrowheads). Areas of necrosis (*) are scattered throughout the solid areas.

Description

Adenocarcinoma, glandular, solid, with early epithelial to mesenchymal transition, mammary gland

Age at Necropsy

179 days

Contributor

Churchill GA (J:112750)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29411
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, glandular, solid, with early epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
179 days