Pathology Image Detail

Caption

 Mammary gland: the mammary gland is expanded and effaced by a large, nodular, encapsulated, densely cellular neoplasm. The center of the neoplasm has undergone necrosis (*). The neoplasm is composed of thick trabeculae and solid areas with various degrees of central necrosis.

Description

 Adenocarcinoma, solid, comedo, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

 285 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29413
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, comedo, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
285 days