Pathology Image Detail

Caption	Area of epithelial to mesenchymal transition: in a few areas, especially at the vicinity of the large areas of coagulation necrosis located at the periphery of the neoplasm, neoplastic cells formed thin trabeculae and cords and gradually became spindloid. The stroma was more abundant and more fibrous in the areas of epithelial to mesenchymal transition than in the rest of the neoplasm.
Description	Adenocarcinoma, solid, comedo, with epithelial to mesenchymal transition, mammary gland
Age at Necropsy	285 days
Contributor	Churchill GA (J:112750)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Synonyms: Adenocarcinoma, solid, comedo, with epithelial to mesenchymal transition, mammary gland

General Note: Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.