Pathology Image Detail

Caption	Mammary gland: the mammary gland and the subcutaneous muscle are expanded by a small, nodular, well-delineated, locally invasive, densely cellular neoplasm. The neoplasm is surrounded by and blends into a large amount of fibrovascular stroma with a mild lymphocytic inflammation. The neoplasm is composed of multiple solid areas (*) separated by glandular areas and with multiple areas representing early stages of epithelial to mesenchymal transition (arrowheads).
Description	Adenocarcinoma, solid, glandular, with early epithelial to mesenchymal transition, mammary gland
Age at Necropsy	250 days
Contributor	Churchill GA (J:112750)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Synonyms: Adenocarcinoma, solid, glandular, with early epithelial to mesenchymal transition, mammary gland

General Note: Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.