Pathology Image Detail

Caption

 Stomach: there is marked diffuse hyperplasia of the gastric mucosa with prominent catarrhal metaplasia. Many gastric glands are moderately to markedly ectatic and are filled with mucus. There is mild diffuse lymphocytic and plasmacytic infiltration of the gastric mucosa. Two gastric glands have herniated underneath the muscularis mucosae.

Description

 Cystic hyperplasia, glandular stomach

Age at Necropsy

 305 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29429
Tumor Name
Stomach - Glandular • hyperplasia - cystic
Treatment Type
None (spontaneous)
Tumor Synonyms
Cystic hyperplasia, glandular stomach
Organ Affected
Stomach - Glandular
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(MMTVTGFA)254Rjc/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated in a (C57BL/6 x DBA/2)F2 genetic background and was subsequently backcrossed to FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(MMTVTGFA)254Rjc/J
FVB-Tgfa
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
305 days