Pathology Image Detail

Caption

 Stomach: this high magnification photomicrograph represents gastric gland herniated underneath the muscularis mucosae. Cells lining the herniated gland do not show atypia or a high mitotic rate. These cells have undergone goblet cell differentiation (catarrhal metaplasia). The herniated gland is not surrounded by a scirrhous reaction.

Description

 Cystic hyperplasia, glandular stomach

Age at Necropsy

 305 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29429
Tumor Name
Stomach - Glandular • hyperplasia - cystic
Treatment Type
None (spontaneous)
Tumor Synonyms
Cystic hyperplasia, glandular stomach
Organ Affected
Stomach - Glandular
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(MMTVTGFA)254Rjc/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated in a (C57BL/6 x DBA/2)F2 genetic background and was subsequently backcrossed to FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(MMTVTGFA)254Rjc/J
FVB-Tgfa
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
305 days