Pathology Image Detail

Caption

Mammary gland: the mammary ducts and alveoli are slightly more prominent than normal for a resting mammary gland. The ducts and the acini are lined by a cuboidal epithelium with an abnormally high mitotic activity. Cells with a morphology consistent with that of "large clear cells" (arrowheads) are more numerous than for a normal 84 days old mouse.

Description

Atypical hyperplasia, mild, mammary gland

Age at Necropsy

84 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29432
Tumor Name
Mammary gland • hyperplasia - atypical
Treatment Type
None (spontaneous)
Tumor Synonyms
Atypical hyperplasia, mild, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(C3-1-TAg)cJeg
Strain Types
transgenic
General Note
Hemizygous mice. The founder of this line carried 6 copies of the transgene. "Line C" was the line maintained by the original investigators for further experiments.
Strain Synonyms
FVB/N-TgN(C3(1)/TAg)3Jeg
FVB/N-TgN(C3-1-TAg)3Jeg
FVB/N-TgN(C3-1-TAg)cJeg
C3(1)/SV40 large T antigen
C3(1)/TAg
C3(1)-TAg
FVB/N C3(1)-TAg
line C
PRP-3
C3(1)/TAG
C3(1)/SV40 TAg
FVB/N C3(1)/TAg
C3(1)SV40 large T antigen
FVB/N C3(1)/TAG
C3(1)/Tag
C3(1)SV40Tag
C3(1)/SV40 Tag
C3(1)/SV40 large T-antigen
C3(1)/SV40 T/t-antigen
C3(1)/TAg+/-
TAG FVB-N
FVB/N C3(1)SV40Tag
C3(1)/SV40 T/t-antigen
C3(1)/simian virus 40 (SV40) T/t-antigens
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
84 days