Pathology Image Detail

Caption	Lung: neoplastic cells have invaded the pulmonary parenchyma. They form anastomosed trabeculae and a few glands supported by a scant amount of fibrovascular stroma. Neoplastic cells at the periphery of neoplastic trabeculae and glands display prominent nuclear palisading, are low columnar, and have an elongated nucleus. Neoplastic cells at the center of neoplastic trabeculae are polygonal with a rounder nucleus than neoplastic cells at the periphery of neoplastic trabeculae.
Description	Mammary adenocarcinoma, metastatic to the lungs
Age at Necropsy	168 days
Contributor	Ward JM (J:107304)
Pathologist	Mikaelian I (J:94320)
Method	H&E

General Note: Hemizygous mice. The founder of this line carried 6 copies of the transgene. "Line C" was the line maintained by the original investigators for further experiments.

Strain Synonyms: FVB/N-TgN(C3(1)/TAg)3Jeg; FVB/N-TgN(C3-1-TAg)3Jeg; FVB/N-TgN(C3-1-TAg)cJeg; C3(1)/SV40 large T antigen; C3(1)/TAg; C3(1)-TAg; FVB/N C3(1)-TAg; line C; PRP-3; C3(1)/T_AG; C3(1)/SV40 TAg; FVB/N C3(1)/TAg; C3(1)SV40 large T antigen; FVB/N C3(1)/T_AG; C3(1)/Tag; C3(1)SV40Tag; C3(1)/SV40 Tag; C3(1)/SV40 large T-antigen; C3(1)/SV40 T/t-antigen; C3(1)/TAg^+/-; T_AG FVB-N; FVB/N C3(1)SV40Tag; C3(1)/SV40 T/t-antigen; C3(1)/simian virus 40 (SV40) T/t-antigens