Pathology Image Detail

Caption	Mammary gland: the mammary gland is effaced by a large, multilobular, encapsulated, densely cellular, mostly expansile, locally invasive, neoplasm with a large central area of cavitation. The neoplasm is predominantly composed of solid areas with secondary lumens that can be discerned even at this low magnification. Areas indicative of epithelial to mesenchymal transition and composed of bundles and fascicles are most prominent at the periphery of the area of cavitation.
Description	Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland
Age at Necropsy	168 days
Contributor	Ward JM (J:107304)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Synonyms: Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland

General Note: Hemizygous mice. The founder of this line carried 6 copies of the transgene. "Line C" was the line maintained by the original investigators for further experiments.

Strain Synonyms: FVB/N-TgN(C3(1)/TAg)3Jeg; FVB/N-TgN(C3-1-TAg)3Jeg; FVB/N-TgN(C3-1-TAg)cJeg; C3(1)/SV40 large T antigen; C3(1)/TAg; C3(1)-TAg; FVB/N C3(1)-TAg; line C; PRP-3; C3(1)/T_AG; C3(1)/SV40 TAg; FVB/N C3(1)/TAg; C3(1)SV40 large T antigen; FVB/N C3(1)/T_AG; C3(1)/Tag; C3(1)SV40Tag; C3(1)/SV40 Tag; C3(1)/SV40 large T-antigen; C3(1)/SV40 T/t-antigen; C3(1)/TAg^+/-; T_AG FVB-N; FVB/N C3(1)SV40Tag; C3(1)/SV40 T/t-antigen; C3(1)/simian virus 40 (SV40) T/t-antigens