Pathology Image Detail

Caption

Solid mammary carcinoma with epithelial to mesenchymal transition: this photomicrograph illustrates a portion of the neoplasm where neoplastic cells gradually become spindloid out of a portion of the neoplasm that is solid (on the right of the photomicrograph). Cells that have undergone epithelial to mesenchymal transition are difficult to differentiate from stromal cells.

Description

Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

168 days

Contributor

Ward JM (J:107304)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29435
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB/N-Tg(C3-1-TAg)cJeg
Strain Types
transgenic
General Note
Hemizygous mice. The founder of this line carried 6 copies of the transgene. "Line C" was the line maintained by the original investigators for further experiments.
Strain Synonyms
FVB/N-TgN(C3(1)/TAg)3Jeg
FVB/N-TgN(C3-1-TAg)3Jeg
FVB/N-TgN(C3-1-TAg)cJeg
C3(1)/SV40 large T antigen
C3(1)/TAg
C3(1)-TAg
FVB/N C3(1)-TAg
line C
PRP-3
C3(1)/TAG
C3(1)/SV40 TAg
FVB/N C3(1)/TAg
C3(1)SV40 large T antigen
FVB/N C3(1)/TAG
C3(1)/Tag
C3(1)SV40Tag
C3(1)/SV40 Tag
C3(1)/SV40 large T-antigen
C3(1)/SV40 T/t-antigen
C3(1)/TAg+/-
TAG FVB-N
FVB/N C3(1)SV40Tag
C3(1)/SV40 T/t-antigen
C3(1)/simian virus 40 (SV40) T/t-antigens
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
168 days