Caption |
Mammary gland: the architecture of the mammary gland is preserved. The lumen of the ducts and alveoli of a few acini is moderately distended by closely-packed neoplastic cells that form solid areas with a few linear clefts. These cells are medium-size, polygonal, with indistinct cell borders and a small amount of amphophilic cytoplasm. The nucleus is central, oval to slightly elongated, medium-size, oval to elongated, normochromatic, with a coarsely clumped chromatin and 1-2 inconspicuous basophilic nucleoli. Anisokaryosis and anisocytosis are mild. A few mitoses are present. Myoepithelial differentiation seems to be present at this stage of the disease. There is mild fibrosis and pleocllular inflammation at the periphery of the affected ducts and acini. |