Caption |
Mammary gland: the mammary gland is effaced by a multilobular, ill-defined, densely cellular neoplasm. This neoplasm is predominantly composed of solid areas that gradually blend into the adjacent fibrovascular stroma. During this process, some neoplastic cells acquired an spindloid phenotype. Neoplastic cells are oat-shaped to spindloid, with indistinct cell borders and a small amount of amphophilic cytoplasm. The nucleus is oval to elongated, normochromatic to slightly hypochromatic, with a clumped to stippled chromatin, and 1-3 small basophilic nucleoli. Anisokaryosis and anisocytosis are mild. Mitoses are numerous. Numerous neoplastic cells undergo single cell necrosis. There is a mild lymphocytic infiltration at the periphery of the neoplasm. |