Pathology Image Detail

Caption	Mammary gland: an intralobular duct and most acini or a mammary lobule are lined by a prominent epithelium. Cells forming this epithelium are cuboidal to polygonal, with a moderate amount of pale basophilic cytoplasm and a medium-size hypochromatic nucleus. Some of these clear cells are surrounded by 2 cells with a small elongated hyperchromatic nucleus oriented at right angle with the basement membrane (arrowheads). Myoepithelial differentiation can still be recognized (arrow).
Description	Atypical ductal hyperplasia, mammary gland
Age at Necropsy	98 days
Contributor	Ward JM (J:107304)
Pathologist	Mikaelian I (J:94320)
Method	H&E

General Note: Hemizygous mice. The founder of this line carried 6 copies of the transgene. "Line C" was the line maintained by the original investigators for further experiments.

Strain Synonyms: FVB/N-TgN(C3(1)/TAg)3Jeg; FVB/N-TgN(C3-1-TAg)3Jeg; FVB/N-TgN(C3-1-TAg)cJeg; C3(1)/SV40 large T antigen; C3(1)/TAg; C3(1)-TAg; FVB/N C3(1)-TAg; line C; PRP-3; C3(1)/T_AG; C3(1)/SV40 TAg; FVB/N C3(1)/TAg; C3(1)SV40 large T antigen; FVB/N C3(1)/T_AG; C3(1)/Tag; C3(1)SV40Tag; C3(1)/SV40 Tag; C3(1)/SV40 large T-antigen; C3(1)/SV40 T/t-antigen; C3(1)/TAg^+/-; T_AG FVB-N; FVB/N C3(1)SV40Tag; C3(1)/SV40 T/t-antigen; C3(1)/simian virus 40 (SV40) T/t-antigens