Caption |
Mammary gland: a mammary lobule is more prominent than nearby lobules. The intralobular ducts and the acini of this lobule are mildly distended by epithelial cells. The center of some solid areas is often necrotic. Cells at the periphery of the lobules are smaller, often slightly attenuated, with a nucleus oriented parallel to the basement membrane, and with a small amount of strongly amphophilic cytoplasm. These features are consistent with myoepithelial differentiation. Cells at the center of the lobules are larger, polygonal, with a moderate amount of pale basophilic cytoplasm and a medium-size hypochromatic nucleus. Mitotic figures are numerous.There is mild interstitial fibrosis. |
