Pathology Image Detail

Caption

 Haired skin: the subcutis is focally expanded by a nodular, well-delineated, expensile, unencapsulated, moderately to densely cellular neoplastic mass.

Description

 Hemangiosarcomas, multiple, subcutis

Age at Necropsy

 71 days

Notes

 This series of photomicrographs illustrates the different histologic phenotypes of subcutaneous hemangiosarcomas in these mice.

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29444
Tumor Name
Blood vessel • hemangiosarcoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Hemangiosarcomas, multiple, subcutis
Organ Affected
Subcutis
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.129S2(B6)-Trp53tm1Tyj/J
Strain Types
congenic
targeted mutation (knockout)
General Note
Congenic mice homozygous for a targeted mutation of Trp53 (p53).
Strain Synonyms
FVB/NJ-Trp53tm1Tyj
FVB.129S2(B6)-Trp53tm1Tyj
FVB/NJ-Trp53tm1Tyj
FVB.129S2(B6)-Trp53tm1Tyj/J
FVB.129S2-Trp53tm1Tyj/J
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
71 days