Caption |
Haired skin: the neoplasm is composed of ill-defined tortuous, interconnected, blood-filled vascular spaces separated by a small amount of fibrovascular stroma and by solid areas composed of neoplastic cells. Cells lining vascular spaces are histiocytoid, large, with indistinct cell borders and with a large amount of acidophilic cytoplasm. The nucleus is central, large to very large, oval, often with a contoured nuclear membrane, occasionally with indentation, with a delicately stippled chromatin and 1-5 small basophilic nucleoli. Anisokaryosis and anisocytosis are prominent. Mitotic rate is intermediate (one tripolar mitosis is detected on this photomicrograph). |
