Pathology Image Detail

Caption

 Lung: large arterial emboli are present. The largest embolus has entirely obstructed the lumen of the artery, ruptured its' wall, and invades the adjacent pulmonary parenchyma.

Description

 Mammary gland, carcinoma, metastatic to the lung

Age at Necropsy

 205 days

Contributor

 Sundberg J (J:94307)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29450
Tumor Name
Mammary gland • carcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
Mammary gland, carcinoma, metastatic to the lung
Organ Affected
Lung
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(MMTVneu)202Mul Trp53tm1Tyj/+
Strain Types
congenic
targeted mutation (knockout)
transgenic
General Note
These mice were carrying the Tg(MMTVneu)202Mul transgene and were heterozygous for the Trp53tm1Tyj allele. They had been backcrossed to FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(MMTVneu)202Mul(Trp53)tm1Tyj
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
205 days