Pathology Image Detail

Caption

This is the exocrine pancreas from a 563 day old male BALB/cByJ mouse. Note the normal acini to the right that consists of small well defined cells. These normal cells have apical granular eosinophilic cytoplasm and basilar nuclei. To the left are cells that are markedly dilated with eosinophilic granules. These are the areas of cytological alteration that some consider to be precancerous or carcinoma in situ like lesions. These rarely progress to neoplasms of the exocrine pancreas. 40x magnification.

Description

Carcinoma in situ from the exocrine pancreas of a 563 day old male BALB/cByJ mouse.

Age at Necropsy

563 days

Notes

Note the normal acini to the right that consists of small well defined cells. These normal cells have apical granular eosinophilic cytoplasm and basilar nuclei. To the left are cells that are markedly dilated with eosinophilic granules. These are the areas commonly called cytological alteration that some consider to be precancerous or carcinoma in situ like lesions. These rarely progress to neoplasms of the exocrine pancreas.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:29365
Tumor Name
Pancreas • carcinoma in situ
Treatment Type
None (spontaneous)
Tumor Synonyms
carcinoma in situ of the pancreas
Organ Affected
Pancreas
Frequency
observed
Reference
J:122261

Strain

Strain
BALB/cByJ
Strain Types
inbred
Strain Synonyms
BALB Bailey
CBy
cBy
Balb/cByJ
BALB
BALB/c
BALB/c Bailey J
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
563 days