Caption |
Dysplasia, hyperplasia and interstitial fibrosis of the mammary gland: most intralobular ducts and most acini are filled by an amorphous acidophilic material. There is moderate to locally marked periacinar and periductular fibrosis. Cells lining mammary acini and ducts do not pile-up but they have more cytoplasm and a larger nucleus than normally. Immunohistochemistry for myoepithelial markers would be needed to determine whether myoepithelial differentiation is maintained in these lesions. |
