Pathology Image Detail

Caption

 Mammary gland: the cells have distinct cell borders and a moderate to large amount of basophilic cytoplasm which often contains variably-sized lipid vacuoles. The nucleus is central, large, hyperchromatic, and with 1-2 large central basophilic nucleoli. A few cells are binucleated. Proteinaceous material is present in the lumen of the macrocyst.

Description

 Macrocyst, mammary gland

Age at Necropsy

 unknown

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 H&E

Model
MMHC ID
MTB:29479
Tumor Name
Mammary gland • cyst - macrocyst
Treatment Type
None (spontaneous)
Tumor Synonyms
Macrocyst, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(MMTVTGFA)254Rjc/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated in a (C57BL/6 x DBA/2)F2 genetic background and was subsequently backcrossed to FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(MMTVTGFA)254Rjc/J
FVB-Tgfa
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown