Pathology Image Detail

Caption

Mammary gland: there is marked multifocal mammary lobular hyperplasia characterized by proliferation of mammary acini which often are distended by a moderate amount of proteinaceous material. The cytoplasm of a variable number of cells in these hyperplastic lobules contain lipids and/or proteins.

Description

Lobular hyperplasia, mammary gland

Age at Necropsy

212 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29480
Tumor Name
Mammary gland • hyperplasia - lobular
Treatment Type
None (spontaneous)
Tumor Synonyms
Lobular hyperplasia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
B6D2-Tg(MMTVTGFA)29Rjc/J
Strain Types
transgenic
General Note
The genetic background of these mice is approximately 50% C57BL/6 and approximately 50% DBA/2. Female mice of this strain are unable to suckle their young.
Strain Synonyms
B6D2-Tg(MMTVTGFA)29Rjc
B6D2-TgN(MMTVTGFA)29Rjc
MMTV-TGFα
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
212 days