Pathology Image Detail

Caption	Mammary gland (mammary lobular hyperplasia): myoepithelial differentiation is evidenced by expression of keratin 5 by a few cells throughout this hyperplastic nodule. These cells are flattened and form a discontinuous layer in the hyperplastic alveoli, while they form a continuous layer in the areas of ductal differentiation (*).
Description	Lobular hyperplasia, mammary gland
Age at Necropsy	212 days
Contributor	Mikaelian I (J:94320)
Pathologist	Mikaelian I (J:94320)
Method	IHC for keratin 5

Image Probes
Type: antibody	Name anti-keratin 5 (PRB-160P) (Covance) Target mouse keratin 5, C-terminus Supplier Covance Notes Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 5 protein, KFVSTTSSSRRSPKS.

General Note: The genetic background of these mice is approximately 50% C57BL/6 and approximately 50% DBA/2. Female mice of this strain are unable to suckle their young.