Pathology Image Detail

Caption

Macrocyst (mammary gland): the epithelium of the cyst is bi-stratified and comprises a discontinuous layer of cells with myoepithelial differentiation.

Description

Macrocyst, mammary gland

Age at Necropsy

29480

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for keratin 5
Image Probes

Type: antibody

Name
anti-keratin 5 (PRB-160P) (Covance)
Target
mouse keratin 5, C-terminus
Supplier
Covance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 5 protein, KFVSTTSSSRRSPKS.

Model

MMHC ID
MTB:29481
Tumor Name
Mammary gland • cyst - macrocyst
Treatment Type
None (spontaneous)
Tumor Synonyms
Macrocyst, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
B6D2-Tg(MMTVTGFA)29Rjc/J
Strain Types
transgenic
General Note
The genetic background of these mice is approximately 50% C57BL/6 and approximately 50% DBA/2. Female mice of this strain are unable to suckle their young.
Strain Synonyms
B6D2-Tg(MMTVTGFA)29Rjc
B6D2-TgN(MMTVTGFA)29Rjc
MMTV-TGFα
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
212 days