Pathology Image Detail

Caption

 Mammary gland - normal tissue. Mammary gland: myoepithelial cells of an interlobular duct and of mammary acini strongly label for keratin 14.

Description

 Mammary gland - Normal tissue. Keratin 14 immunohistochemistry.

Age at Necropsy

 73 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 IHC for keratin 14
Image Probes

Type: antibody
Name
anti-keratin 14 (PRB-155P)
Target
mouse keratin 14, C-terminus
Supplier
Biolegend, formerly Covance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 14 protein, KVVSTHEQVLRTKN.

Model
MMHC ID
MTB:29485
Tumor Name
Mammary gland • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary gland, normal tissue
Organ Affected
Mammary gland
Frequency
not applicable
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(Wnt1)1Hev/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated on a C57BL/6 x SJL background. It was subsequently backcrossed onto FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(Wnt1)1Hev/J
FVB-Wnt1
FVB/NJ-Tg(Wnt1)1Hev/J; FVB-Wnt1
MMTV-Wnt-1 FVB/NJ
MMTV-Wnt-1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
73 days