Caption |
Mammary gland: the neoplasm is composed of radiating and branching ducts terminated by club-shaped masses of cells which caricature the terminal end bud of the developing mammary gland. Labeling for keratin 6 is restricted to suprabasal cells in the areas of ductal differentiation. |
Description |
Carcinoma, tubular, solid (type P tumor), mammary gland |
Age at Necropsy |
422 days |
Notes |
This type of neoplasm is named "type P tumor" in accordance to the current literature. Myoepithelial differentiation is a prominent feature of "type P tumors". Immunolabeling for keratin 17 of "type P tumors" is consistent with the pattern of differentiation named by some authors "follicular/epidermal transdifferentiation". |
Contributor |
Churchill GA (J:112750) |
Pathologist |
Mikaelian I (J:94320) |
Method |
IHC for keratin 6 |
