Caption |
Mammary gland: labeling for keratin 17 is predominantly detected in suprabasal cells in the areas of ductal differentiation. This pattern of labeling mimics that of the normal outer root sheath of the hair follicle. |
Description |
Carcinoma, tubular, solid (type P tumor), mammary gland |
Age at Necropsy |
422 days |
Notes |
This type of neoplasm is named "type P tumor" in accordance to the current literature. Myoepithelial differentiation is a prominent feature of "type P tumors". Immunolabeling for keratin 17 of "type P tumors" is consistent with the pattern of differentiation named by some authors "follicular/epidermal transdifferentiation". |
Contributor |
Churchill GA (J:112750) |
Pathologist |
Mikaelian I (J:94320) |
Method |
IHC for keratin 17 |