Pathology Image Detail

Caption

 Haired skin - normal tissue. Haired skin: there is strong labeling of the outer root sheath for keratin 17.

Description

 Haired skin - Normal tissue. Keratin 17 immunohistochemistry.

Age at Necropsy

 422 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 IHC for keratin 17
Image Probes

Type: antibody
Name
anti-keratin 17
Target
mouse and human keratin 17 (recombinant, C terminal)
Notes
polyclonal rabbit anti-mouse keratin 17 antibody (kind gift of Dr. Pierre Coulombe, Johns Hopkins University School of Medicine)

Model
MMHC ID
MTB:29487
Tumor Name
Skin • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
haired skin, normal tissue
Organ Affected
Skin
Frequency
not applicable
Reference
J:94320

Strain
Strain
FVB.Cg-Tg(Wnt1)1Hev/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The transgene was generated on a C57BL/6 x SJL background. It was subsequently backcrossed onto FVB/NJ.
Strain Synonyms
FVB/NJ-Tg(Wnt1)1Hev/J
FVB-Wnt1
FVB/NJ-Tg(Wnt1)1Hev/J; FVB-Wnt1
MMTV-Wnt-1 FVB/NJ
MMTV-Wnt-1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
422 days