Pathology Image Detail

Caption

 Mammary gland: two cells (arrowheads) with a myoepithelial phenotype label strongly for keratin 14. All other neoplastic cells fail to label for keratin 14.

Description

 Carcinoma, solid, mammary gland

Age at Necropsy

 269 days

Contributor

 Churchill GA (J:112750)

Pathologist

 Mikaelian I (J:94320)

Method

 IHC for keratin 14
Image Probes

Type: antibody
Name
anti-keratin 14 (PRB-155P)
Target
mouse keratin 14, C-terminus
Supplier
Biolegend, formerly Covance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 14 protein, KVVSTHEQVLRTKN.

Model
MMHC ID
MTB:29489
Tumor Name
Mammary gland • carcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Carcinoma, solid, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
FVB/N-Tg(MMTVneu)202Mul/J
Strain Types
transgenic
General Note
Homozygous mice
Strain Synonyms
FVB/N-TgN(MMTVneu)202Mul
MMTV neu
FVBN202
FVBN202 neu
MMTV-erbB2
FVB-Neu
MMTV-Neu
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
269 days